Mucosal expression profiling in patients with inflammatory bowel disease before and after first infliximab treatment
Microarray 1-colour mRNA
Organism:
Homo sapiens
Array Design(s):
Publication
- Arijs I, De Hertogh G, Lemaire K, Quintens R, Van Lommel L et al. (2009) Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment.
Analysis Methods
Normalization | RMA using oligo version 1.36.1. arrayNormalization.R. |
Differential expression statistics | Moderated t-statistics computed with limma version 3.28.21. Independent filtering performed using genefilter version 1.54.2, with gene variances as filter statistic. p-values adjusted using Benjamini & Hochberg (1995) FDR correction. By default, significant differential expression called if adjusted p <= 0.05. |
Gene Set Enrichment Analysis | Fisher (non-directional), FDR < 0.05 using piano version 1.10.2. |
Resources
